Description About Edaravone CAS:89-25-8 :
Edaravone (brand name ラジカット, Radicut) is a nootropic and neuroprotective agent used for the purpose of aiding neurological recovery following acute brain ischemia and subsequent cerebral infarction. It acts as a potent antioxidant and strongly scavenges free radicals, protecting against oxidative stress and neuronal apoptosis. It has been marketed solely in Japan by Mitsubishi Pharma since 2001. It is also marketed in India by Edinburgh Pharmaceuticals by the brand name Arone.
On June 26, 2015, Mitsubishi Tanabe Pharma Corporation announced it has received approval to market Radicut for treatment of ALS in Japan. The phase III clinical trial began in 2011 in Japan. The company was awarded Orphan Drug Designation for Radicut by the FDA and EU in 2015. Radicut is an intravenous drug and administrated 14 days followed by 14 days drug holiday.
The biotech company Treeway is developing an oral formulation of edaravone (TW001) and is currently in clinical development. Treeway was awarded orphan drug designation for edaravone by the EMA in November 2014 and FDA in January 2015.Hot tags: 4-Aminopyridine .
Edaravone has been shown to attenuate methamphetamine- and 6-OHDA-induced dopaminergic neurotoxicity in the striatum and substantia nigra, and does not affect methamphetamine-induced dopamine release or hyperthermia. It has also been demonstrated to protect against MPTP-mediated dopaminergic neurotoxicity to the substantia nigra, though notably not to the striatum.
Competitive Advantage :
1 High quality with competitive price :
1) Quality Standard: USP 35
2) Purity: >99%
3) We are manufacturer and can provide high quality products with factory price.
2 Fast and safe delivery :
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3 We have clients throughout the world :
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
4 Three Principles :
1)Safe delivery: Channel diversification,protect the privacy of customers.And just in case, ensure to re-ship.
2)Never change: The product will always maintain high purity, will not change,High quality is the culture of our company.
3)Good services: As quickly as possible to solve customer problems, so that customers receive the goods safely.
|Chemical Name||PMP; Edaravone; 5-Methyl-2-phenyl-1,2- dihydropyrazol-3-one; 2,4-dihydro-5-methyl-2-phenyl-3h-pyrazol-3-one; C.I. Developer 1; MCI-186; 1-Phenyl-3-Methyl-5-Pyrazole; 1,3,5-PMP; 1- Phenyl-3-Methyl-5-Pyrazolone; 1-Phenyl-3-Methyl-5-Prazalone; 3-Methyl-1-phenyl-5-pyrazolone|
|Boiling Point||333°C at 760 mmHg|
|Description||White or off white or light yellow crystalline powder|
|Package||Security and diversification|
|Minimum Order Quantity||10g|
Edaravone Chemical Properties