Modafinil powder is a wakefulness-promoting drug used for treatment of disorders such as narcolepsy, shift work sleep disorder, and excessive daytime sleepiness associated with obstructive sleep apnea. It has also seen widespread off-label use as a purported cognitive enhancer.
In English-speaking countries it is sold under the brand names Alertec, Modavigil, and Provigil. In the United States Modafinil powder is classified as a schedule IV controlled substance and restricted in availability and usage, due to concerns about possible addiction potential. In most other countries it is a prescription drug but not otherwise legally restricted.
Modafinil powder acts as an atypical, selective, and weak dopamine reuptake inhibitor which indirectly activates the release of orexin neuropeptides and histamine from the lateral hypothalamus and tuberomammillary nucleus, respectively, by unknown mechanisms, all of which contribute to heightened arousal.
Modafinil powder targets dopaminergic neurons in the hypothalamus of the brain which creates orexin, hypocretin, and dopamine, thereby elevating mood, alertness, and energy levels. Studies have shown that when the release of dopamine is stimulated by exercise, exhilaration, and diet individuals tend to experience increased happiness, greater concentration, and a heightened sense of fulfillment. However, due to various cognitive dysfunctions,
many individuals are unable to naturally produce sufficient amounts of dopamine resulting in deficiencies and disorders that can be improved with a proper dosage of Modafinil powder. To maximize the effectiveness of Modafinil and prevent your body from building a tolerance for the drug, you should take Modafinil powder at your prescribed dosage only one to three times a week. Under normal circumstances, patients will feel slight improvement after the first few doses, with the positive effects becoming more and more pronounced as the medication builds up in their body. The short term effects (and the effects most desired by individuals using Modafinil to enhance performance) wear off after about ten hours.
The benefits of Modafinil powder are manifold and have been researched extensively over the past decade. Partially, this is due to the military and government interest in modafinil as a tool for soldiers and pilots who engage in combat activity under sleep-deprived conditions.
According to multiple studies, there is a significant decrease in fatigue when using Modafinil powder. Users that experience sleep deprivation or have hyperinsomnia find that their mental performance is heightened after using modafinil (or the downsides are negated).
Another benefit of modafinil is with regard to general cognitive abilities. Modafinil can improve cognitive abilities, which are measured by reaction time, working memory, and other tests. While the benefits are less for non-sleep deprived individuals, it is obvious that healthy adults can still see cognitive benefits from using modafinil.
One of the favorite uses for modafinil is attention, alertness, and concentration. While all of these are similar in their mechanisms as “wakefulness”, they are slightly different from a scientific perspective. The quantity of research literature shows that modafinil has a positive impact on all of these factors.
Technically, Modafinil powder is considered a “wakefulness agent” rather than a stimulant, but many in the nootropics community use it as a powerful tool for concentration and focus. It is considered one of the more famous and heavily consumed nootropics, which has spread into Silicon Valley entrepreneur circles, Wall Street traders, and a variety of other high performance individuals.
Developed initially as a treatment for narcolepsy, Modafinil powder has a positive effect on cognition and cognitive abilities while also improving concentration and focus. Scientists hypothesize that modafinil is effective because it increases adrenaline and dopamine neurotransmission enough for these cognitive advantages, but not enough to create euphoria and addiction.
Due to conversations between famed biohacker Dave Asprey and author, Tim Ferriss, Modafinil powder has grown in popularity as a smart drug. Beyond public consumption, it is also used by the military as an alternative to Adderall and wakefulness agent for sleep deprived soldiers.
Although some people are “non-responders” to Modafinil powder, most people record feeling a sense of focus and cognitive enhanceme
There are so many studies on Modafinil powder, the dosage varies greatly depending on the goal. Some studies with amphetamine comparisons use up to 400 mg of the drug, wh
ile studies with children and ADHD use as little as 170 mg. The standard doses (produced by drug companies) is between 100–200 mg.
Most starting recommended doses are 200 mg, but Modafinil powder is a powerful drug and might warrant half that dose (100 mg) to test the waters.
Since Modafinil is designed to keep users awake and alert over the course of 9-10 hours, the ideal time to take Modafinil is in the morning prior to starting your day or 2-3 hours before starting a shift. This medication can be taken with or without food and is usually started with a 12 week or less prescription that will be reviewed on a regular basis before moving forward.
Due to its interactions with other medications, Modafinil should not be shared with friends and family who do not have prescriptions. And if you do decide to purchase it online instead of going through your medical provider, be sure to discuss your use with your doctor before taking any other prescribed medications. It can be stored at room temperature in a dry location and should be kept out of the reach of children. Regardless of their condition, nearly all adult patients are prescribed the same 200 mg/day dose. This drug is considered to be the last option for children as it has been shown to produce adverse psychiatric and dermatologic effects.
You should not use this medication if you are allergic to Modafinil powder or armodafinil (Nuvigil).
Before using Modafinil powder, tell your doctor if you have angina (chest pain), liver or kidney disease, a heart problem, a history of drug addiction, if you take blood pressure medication, or if you have recently had a heart attack.
Modafinil powder affects the central nervous system. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid other dangerous activities until you know how this medication will affect your level of wakefulness.
Stop taking modafinil and call your doctor if you have a skin rash, no matter how mild. A medicine similar to modafinil has caused severe skin reactions serious enough to require hospitalization. Other signs of a severe reaction include fever, sore throat, headache, and vomiting with a severe blistering, peeling, and red skin rash.
There may be other drugs that can interact with modafinil. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Powerful nootropics and smart drugs often have side effects. The side effects of Modafinil powder are often related to appetite. Many people experience a lower appetite when they take modafinil, which translates to weight loss in some. While this might be considered a positive benefit of modafinil to some, it is a side effect of the drug nonetheless.
Other Modafinil powder side effects include headaches, dizziness, and irritability, which are rare and can depend on many factors. Sometimes they are a result of an increased heart rate and blood pressure, which is another side effect of modafinil. Rarely, people experience nausea, dry mouth, and abdominal pain.
Naturally, because Modafinil powder is a wakefulness agent, taking the drug too late at night will negatively impact sleep. It can cause insomnia in some people.
While Modafinil powder has been shown to produce severe side effects in some individuals, they are extremely rare. If you experience an allergic reaction with symptoms that include skin rash, blistering, peeling, mouth sores, fever, shortness of breath, leg swelling, or jaundice, stop taking Modafinil and call your doctor immediately.
Since this medication manipulates brain chemistry, there are other side effects that, if present, should be an immediate red flag to stop taking it. These include hallucinations, depression, anxiety, chest pains, trouble breathing, unusual thoughts and aggressive behavior, and suicidal thoughts. While the above side effects are uncommon, there are a number of more common side effects that you might experience when using Modafinil powder for the first few times. Less severe side effects include headaches,
back pain, dizziness, nausea, upset stomach, diarrhea, insomnia, stuffy nose. These side effects may require your dosage be modified, or that you be changed to a different medication. As I mentioned before, Modafinil powder manipulates your brain’s chemistry which can lead to possibly the most common “side effect” of all, a robot-like state of workaholism. A friend of mine with a prescription for Modafinil powder once told me that he will often find himself “…In a state of emotionless focus.
I didn’t want to do anything except work. My appetite, libido, and desire to ‘goof off’ disappeared and were replaced by a steady state of focus.” While some of you might be drawn to the drug for the purpose of robot-like focus, I have had a number of acquaintances report that they felt less compassionate, loving, and empathetic while using Modafinil powder so keep this in mind before beginning your dose.
The benefits seen by taking Modafinil powder will depend on your individual symptoms or goals when using the drug. While some patients experience life changing side effects and the elimination of crippling sleep disorders, other users experience effects that are less remarkable but still beneficial. Commonly Recorded Benefits for “Normal” Patients: Here are some of the most commonly recorded benefits by patients taking Modafinil to combat destructive sleep disorders.
Improved Job Satisfaction: It is difficult to hold onto a job or regular income when you are unable to remain awake for more than a few moments at a time. This is especially true in today’s knowledge economy, where our attention is precious. Taking Modafinil powder keeps you awake and able to function normally enabling you to have a functional work life.
Socializing: Our relationships give meaning to our lives, but it’s not always easy to be care-free and relaxed, even around friends. To maintain a healthy social circle participation is mandatory. Unfortunately, when you are too tired to function, participating in any social event becomes all but impossible. Taking Modafinil powder allows you to be more engaged in other aspects of life that you may have been missing out on, and be more social as a result.
Home Life: Raising a healthy family and experiencing a fulfilling home life takes work, and when you are chronically tired or depressed it can feel overwhelming, even impossible to do everything else and still make time for your children and spouse.. Modafinil powder helps relieve depression and increase your energy levels so that you can connect with those you love in a healthier and more consistent manner.
Modafinil’s clinical benefits can be distilled down to one phrase… Physical homeostasis. In other words, it helps rebalance and recalibrate your brain and body, negating the effects of disruptive sleep disorders and allowing you to live a normal life again or for the first time.
Commonly Recorded Benefits for Performance Focused Patients
Just because you need a prescription to legally possess Modafinil powder doesn’t necessarily mean that narcolepsy is your primary reason for requesting a prescription. Since Modafinil has a wide number of applications, it’s actually pretty easy to get a prescription from your doctor as long as you have some kind of legitimate need. For example, I know of several freelancers who work with overseas clients and use Modafinil powder to help them stay awake and alert during their abnormal work hours.
I also know of plenty of entrepreneurs and startup employees who convince their local doctor to give them a prescription to help with the ridiculous work loads they are facing. Since these individuals don’t technically suffer from a sleep disorder, I wanted to discuss the performance related benefits separate from clinical benefits.
Increased Productivity: The most common benefit that I found reported from a wide variety of high achieving individuals is an increase in productivity. Some claim that it gives them laser like focus, others that it simply balances their energy levels, but nearly everyone who uses Modafinil powder reports some sort of increase in their motivation and productivity.
Increased Mental Endurance: One of the most difficult parts about being a knowledge worker is trying to operate at full capacity for hours on end. Modafinil powder seems to provide a quick solution. Nearly everyone I know who has tried the drug claims that they were able to work far longer than normal while maintaining their productivity over the long hours.
Improves Decision Making: Another commonly reported benefit is that Modafinil helps man people improve their decision making. Or rather, it helps them reduce their propensity to make impulsive or otherwise “bad” decisions.
While most of the studies associated claiming these benefits dealt with smaller sample sizes and require further research, there is enough scientific and anecdotal evidence to suggest that Modafinil is indeed an effective substance for enhancing personal performance.
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